1UP Dispensary Brings Curated Cannabis Retail Experience to Historic Route 66 Corridor in Downtown Albuquerque

Image credit: Image provided courtesy of 1UP Dispensary

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A new cannabis dispensary, 1UP Dispensary, has opened in downtown Albuquerque on the historic Route 66 corridor, offering both recreational and medical cannabis products. Located at a busy intersection, the dispensary aims to integrate into the local community and contribute to the area's revitalisation. This development reflects a trend of cannabis retailers moving into established commercial districts, boosting local tax revenue and employment.

Press Release

ALBUQUERQUE, NM - April 14, 2026

A new licensed cannabis dispensary is establishing its presence in the heart of downtown Albuquerque, offering residents and visitors a curated retail experience along one of the most iconic roadways in American history.

1UP Dispensary, located at 301 Central Ave NW on the corner of Third Street and Central Avenue, has opened its doors at a prominent intersection along the historic Route 66 corridor. The dispensary serves both recreational and medical cannabis consumers in New Mexico’s largest city.

The retail location occupies a visible storefront in a well-trafficked area of downtown Albuquerque, positioning the business within walking distance of local restaurants, galleries, and entertainment venues. The dispensary’s placement reflects a growing trend of licensed cannabis retailers integrating into established commercial districts rather than operating on the outskirts of urban centers.

“Our goal from the beginning was to be part of the downtown community, not separate from it,” said Brandon Heckman, owner of 1UP Dispensary. “Central Avenue has a long tradition of local businesses serving the people who live and work here, and we want to continue that tradition.”

1UP Dispensary offers a curated selection of premium cannabis products, including flower, edibles, concentrates, and pre-rolls sourced from licensed producers across New Mexico. Staff members provide guided consultations for customers seeking specific effects or product recommendations.

New Mexico’s regulated cannabis market has expanded significantly since recreational sales began in the state, with licensed dispensaries contributing to local tax revenue and employment. Downtown Albuquerque has seen several new retail and hospitality businesses open in recent months as the area continues its revitalization.

The dispensary is open seven days a week and serves customers aged 21 and older for recreational purchases, as well as registered medical cannabis patients. Additional information about products and hours of operation is available at www.1upabq.com.

Notes to editors

About 1UP Dispensary: 1UP Dispensary is a licensed cannabis retail store located at 301 Central Ave NW in downtown Albuquerque, New Mexico, on the historic Route 66 corridor. The dispensary offers a curated selection of premium recreational and medical cannabis products, including locally grown flower, edibles, concentrates, and pre-rolls. Open daily from 10am to 11pm, 1UP Dispensary serves customers aged 21 and older as well as registered medical cannabis patients. For more information, visit www.1upabq.com or call (505) 270-1207.

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