A new licensed cannabis dispensary is establishing its presence in the heart of downtown Albuquerque, offering residents and visitors a curated retail experience along one of the most iconic roadways in American history.
1UP Dispensary, located at 301 Central Ave NW on the corner of Third Street and Central Avenue, has opened its doors at a prominent intersection along the historic Route 66 corridor. The dispensary serves both recreational and medical cannabis consumers in New Mexico’s largest city.
The retail location occupies a visible storefront in a well-trafficked area of downtown Albuquerque, positioning the business within walking distance of local restaurants, galleries, and entertainment venues. The dispensary’s placement reflects a growing trend of licensed cannabis retailers integrating into established commercial districts rather than operating on the outskirts of urban centers.
“Our goal from the beginning was to be part of the downtown community, not separate from it,” said Brandon Heckman, owner of 1UP Dispensary. “Central Avenue has a long tradition of local businesses serving the people who live and work here, and we want to continue that tradition.”
1UP Dispensary offers a curated selection of premium cannabis products, including flower, edibles, concentrates, and pre-rolls sourced from licensed producers across New Mexico. Staff members provide guided consultations for customers seeking specific effects or product recommendations.
New Mexico’s regulated cannabis market has expanded significantly since recreational sales began in the state, with licensed dispensaries contributing to local tax revenue and employment. Downtown Albuquerque has seen several new retail and hospitality businesses open in recent months as the area continues its revitalization.
The dispensary is open seven days a week and serves customers aged 21 and older for recreational purchases, as well as registered medical cannabis patients. Additional information about products and hours of operation is available at www.1upabq.com.


