EyeCool Therapeutics Announces Publication of Category III CPT® Code 1115T for Ocular Cooling

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EyeCool Therapeutics announced that the American Medical Association has published a new Category III CPT code, 1115T, for an ocular cooling procedure related to their investigational technology. This code, effective January 1, 2027, will help track and report the procedure as EyeCool develops its ETX-4143 device for treating chronic ocular surface pain. The publication of this code is a significant step in establishing the clinical and reimbursement framework for this emerging therapeutic category.

EDITORIAL INSIGHT: Context, industry insight and market perspectives of this news story

The publication of a dedicated Category III CPT code for an ocular cooling procedure marks a procedural step for EyeCool Therapeutics as it works to advance its investigational technology for chronic ocular surface pain. While the code does not confer regulatory approval or guarantee reimbursement, it represents formal recognition of the procedure within the medical coding system, enabling clinicians and researchers to report and track its use as supporting evidence is gathered.

For companies operating in the medical device sector, the introduction of a Category III CPT code is often a necessary precursor to broader clinical adoption and eventual consideration for insurance coverage. As EyeCool continues its clinical development programme, the new code may help facilitate data collection and support future discussions with payers, though commercial and regulatory milestones remain ahead.

Story Ideas
Regulation

Implications of New CPT Code for Ocular Cooling Procedures on Future Medical Billing and Insurance

The publication of CPT code 1115T for ocular cooling by the AMA indicates potential shifts in medical billing practices and insurance coverage for this emerging technology, although it does not guarantee insurance payment or FDA approval.

Target audience
healthcare policy analysts and medical billing professionals
Story potential
7/10
Technology

Potential Impact of Ocular Cooling Technology on Treatment for Chronic Ocular Surface Pain

EyeCool's new CPT code for ocular cooling could signal advancements in treatments for chronic ocular surface pain, a condition with limited options, by standardising the procedure for clinical trials and data collection.

Target audience
medical and technology news outlets
Story potential
6/10
Press Release

CAMBRIDGE, MA - October 8, 2026

EyeCool Therapeutics, Inc. (“EyeCool” or the “Company”), a clinical-stage medical device company pioneering precision ocular cooling as a potential new therapeutic category for chronic ocular surface pain, today announced that the American Medical Association (AMA) has published Category III Current Procedural Terminology (CPT®) code 1115T for an ocular cooling procedure relevant to the Company’s investigational technology.

The new code follows acceptance of EyeCool’s application by the AMA’s CPT Editorial Panel at its September 2026 meeting. Code 1115T describes transconjunctival cooling directed to the long ciliary nerves for ocular pain. The code is scheduled to become effective on January 1, 2027.

Publication of the code represents an important milestone in the development of the clinical and reimbursement infrastructure for ocular surface cooling. Category III CPT codes provide a mechanism for reporting emerging technologies, procedures, and services and can support the collection of utilization data as clinical evidence develops.

“Publication of a dedicated Category III CPT code for ocular cooling is an important step in the development of this potential new therapeutic category,” said Ruben F. Salinas, PhD, President and Chief Executive Officer of EyeCool Therapeutics. “Once effective, code 1115T will provide a standardized mechanism to identify and track the procedure, adding an important piece of infrastructure as we continue advancing the ETX-4143 device through clinical development.”

EyeCool is developing ETX-4143, an investigational in-office device designed to deliver controlled, localized cooling to the ocular surface. The Company is evaluating the technology as a potential treatment for chronic ocular surface pain (COSP).

The coding milestone follows EyeCool’s continued development of the scientific and clinical foundation for precision ocular cooling, including published clinical studies evaluating ETX-4143. The Company is preparing for the next stage of U.S. clinical development.

Category III CPT codes do not establish or guarantee insurance coverage or payment, and inclusion in the CPT code set does not constitute AMA endorsement of a procedure. Publication of the code does not constitute FDA approval or clearance of EyeCool’s investigational device. Code 1115T is not reportable before its effective date.

Notes to editors

About EyeCool Therapeutics EyeCool Therapeutics is a clinical-stage medical device company pioneering precision ocular cooling as a potential new therapeutic category for chronic ocular surface pain. The Company is advancing ETX-4143, an investigational in-office cooling device being evaluated as a potential treatment for chronic ocular surface pain. For more information, please visit www.eyecooltx.com. Investigational Device Disclosure Warning: This product has not been approved or cleared for marketing by the U.S. Food and Drug Administration and is considered an investigational device. CPT® is a registered trademark of the American Medical Association.

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